Anti-hypoxic agents work by improving oxygen utilization, increasing circulation, and protecting cells from damage caused by oxidative stress during periods of low oxygen availability. Herbs with anti-hypoxic properties are often adaptogens or circulatory enhancers. Rhodiola rosea is renowned for its ability to support oxygen efficiency and endurance in high-altitude or stress-induced low oxygen conditions. Ginkgo biloba promotes improved blood flow to tissues, helping deliver oxygen more effectively. Reishi mushroom (Ganoderma lucidum) is another potent anti-hypoxic herb, known for its immune-enhancing and oxygen-regulating properties. These herbs offer natural support for resilience in physically demanding or low-oxygen environments.