Nephroprotective agents are used to shield the kidneys from harm caused by toxins, infections, or chronic conditions such as diabetes or hypertension. These substances work by reducing inflammation, enhancing detoxification, and improving cellular repair within the kidneys. Herbal remedies like nettle (Urtica dioica), turmeric (Curcuma longa), and reishi mushroom (Ganoderma lucidum) are often employed for their nephroprotective properties. Adequate hydration and dietary support are also key components of protecting kidney health.