Parturifacients are traditionally used in the final stages of pregnancy to encourage the onset of labor or strengthen uterine contractions. These substances are typically employed under the guidance of a trained practitioner due to their potent effects. Herbal examples include blue cohosh (Caulophyllum thalictroides) and black cohosh (Actaea racemosa), which have been used historically to prepare the uterus for childbirth. Modern use emphasizes caution, as improper use or timing can pose risks to both the birthing individual and the baby.

Safe and effective parturifacients should always be used under the supervision of a qualified healthcare provider or midwife to ensure safety and optimal outcomes.